Chien-Chang Lee assumed the role of Chief Information Officer (CIO) for the Taiwan Ministry of Health and Welfare (MOHW) on January 16, 2024. Prior to this appointment, Chien-Chang held positions of distinction, including Professor of Emergency Medicine and Deputy Director of the Center of Intelligent Healthcare at National Taiwan University (NTU) Hospital. His journey in medicine began at NTU, where he completed his medical education and residency in emergency medicine before pursuing a doctorate in health data science at Harvard University, driven by his deep-seated commitment to clinical and population research.

As CIO, Chien-Chang oversees the information technology (IT) systems and security activities for a workforce exceeding 5,300 individuals. He spearheads the development and implementation of IT policies, manages critical projects, and strategically guides IT investments, aligning with the MOHW’s mission to advance the health and well-being of the Taiwanese population. Chien-Chang also manages the department’s substantial health IT budget.

Before his role as CIO, Chien-Chang served as the deputy director of the Center of Intelligent Healthcare at NTU since March 2020. In this capacity, he provided strategic direction for the integration of artificial intelligence (AI) into clinical settings, offering expertise in policy development, budgeting, innovation, and risk management.

Beyond his administrative roles, Chien-Chang’s contributions to medicine are profound. As a Staff Physician in Emergency Medicine and Professor of Emergency Medicine, he provided critical care to emergency department patients and oversaw operations at a dynamic Biomedical Data Science lab. His research encompasses translational diagnostic medicine, big data epidemiology, computational biology, evidence-based medicine, and AI in clinical practice. Notably, his groundbreaking research on the association between fluoroquinolone antibiotics and aortic dissections and aneurysm ruptures prompted regulatory action by the United States Food and Drug Administration (FDA), leading to global revisions in antibiotic prescription guidelines.

Stanford University recognized Chien-Chang as one of the top 2% scientists worldwide from 2021 to 2023, reflecting his prolific publication record comprising 250 scientific papers, over 11,000 citations, and an impressive H-index of 56.

Education

Education

M.D. National Taiwan University

M. Sc. National Taiwan University

Sc. D. Harvard School of Public Health

Certificate: Global Faculty in Training of Biodesign, Stanford University

Selected Award in Recent Years

1. 2024 Edison Awards, Fort Myer, FL USA
2. 2022 Future technology innovation award, National Science Council, Taiwan
3. 2021 Top 2% Scientist in the World, Stanford University
4. 2020 Mentor, Best Presentation Award, MIT-NUS international datathon
5. 2019 Kyorin Award of Taipei Medical Association
6. 2018 Travel Grant Award, Korean Society of Critical Care Medicine
7. 2017 Best Research Award, European Society of Intensive Care Medicine
8. 2016 Best Oral Presentation Award, Taiwan Society of Emergency Medicine
9. 2015 Best Big Health Data Application Proposal 2, Ministry of Technology
10. 2013 Best Young Investigator Award, National Taiwan University Hospital

Board of Editors (Selected)

Editor-in-Chief: Emergency Medicine-Open Journal

Associate editor: Journal of Acute Medicine, Frontier in Genetics

Reviewers (Selected journals):

JACC, Journal of Acute College of Cardiology, BMJ Open, Chest, JAMA Internal Medicine, Clinical Microbiology & Infection, Value in Health

Full list of publications (Google Scholar)

https://scholar.google.com/citations?user=tnwTwGMAAAAJ&hl=en

Selected publications

1. YC Hsein, IJ Wu, Lee CC. Serum levels of copeptin predict adverse outcomes and improve risk prediction of TRISS and MGAP scores in patients with multiple trauma: A single-center prospective cohort study Journal of trauma and acute care surgery 2023, 94 (2), 336-343
2. WT Hsu, YT Lee, J Tan, Lee CC, Genome–phenome wide association study of broadly defined headache Brain Communications 5 (3), fcad167
3. Park JY, Hsu TC, Hu JR, Chen CY, Hsu WT, Lee M, Ho J, Lee CC. Predicting Sepsis Mortality in a Population-Based National Database: Machine Learning Approach. J Med Internet Res. 2022 Apr 13;24(4):e29982.
4. Lee CC, Lee MG, Huang IH, Tan J, McCaw ZR, Su KY, Hsu TC, Huang RYJ, Kuo PH, Chen SC; National Taiwan University Hospital, Health Data Science Research Group. Genome-wide association study of primary dysmenorrhea in the Taiwan Biobank validates associations near the NGF and IL1 gene loci. J Hum Genet. 2022 Aug;67(8):449-458.
5. Huang AH, Hsu WT, Lee CC. Respiratory virus burden in the community: more than what meets the eye. Clin Infect Dis. 2022
6. Chiang CH, Chiang CH, Pickering JW, Stoyanov KM, Chew DP, Neumann JT, Ojeda F, Sörensen NA, Su KY, Kavsak P, Worster A, Inoue K, Lee CC. Performance of the European Society of Cardiology 0/1-Hour, 0/2-Hour, and 0/3-Hour Algorithms for Rapid Triage of Acute Myocardial Infarction : An International Collaborative Meta-analysis. Ann Intern Med. 2022 Jan;175(1):101-113.
7. Liu MA, Hsu WT, Johnstone C, Chang A, Nguyen J, Lee CC. Interpreting the Clinical Utility of Early Interdisciplinary Supportive Care for Untreated Metastatic Esophageal Cancer. J Clin Oncol. 2021 Aug 1;39(22):2518.
8. Lee CC, Kwa ALH, Apisarnthanarak A, Feng JY, Gluck EH, Ito A, Karuniawati A, Periyasamy P, Pratumvinit B, Sharma J, Solante R, Swaminathan S, Tyagi N, Vu DM, Zirpe K, Schuetz P. Procalcitonin (PCT)-guided antibiotic stewardship in Asia-Pacific countries: adaptation based on an expert consensus meeting. Clin Chem Lab Med. 2020 Jan 13
9. Lee CC, Chang JC, Mao XW. Combining Procalcitonin and Rapid Multiplex Respiratory Virus Testing for Antibiotic Stewardship in Older Adult Patients with Severe Acute Respiratory Infection. J Am Med Dir Assoc. 2020 Jan;21(1):62-67.
10. Lee CC, Hsieh R, Porta L, Oral Fluoroquinolone and the Risk of Aortic Dissection. J Am Coll Cardiol. 2018 Sep 18;72(12):1369-1378 2018.